Showing posts with label H5N1. Show all posts
Showing posts with label H5N1. Show all posts

Monday, January 7, 2013

Fluageddon: The coming killer epidemic!



In the fall of the year 1918, a bad and terrible flu swept over the planet killing more people in America than were killed in the last century of warfare combined. As many as 50 million worldwide died horrible deaths as they either slowly drowned from fluids that filled their lungs or from other complications. Yes, influenza can and has enacted terrible suffering worldwide; a scenario continues to this day.

In America alone, the CDC has estimated that over a period of 30 years, between 1976 and 2006, flu-associated deaths in the United States range from a low of about 3,000 to a high of about 49,000 people. But, that’s not the scary part!

Not counting the pandemic outbreak of the Swine flu, it’s now been over forty years since the world has seen a novel or new version of the flu. Fortunately, the influenza type Swine Flu (type A H1N1) was not very serious, but on a more ominous note it was highly contagious. In just three weeks, after first appearing in Mexico, the Swine Flu was seen in 20 countries on five continents! After just the first year, it has been estimated that 1 in 7 people have been exposed. And, even though this flu was relatively mild, it still managed to kill a lot of people. One study estimated that ‘globally there were 201,200 respiratory deaths (range 105,700—395,600) with an additional 83,300 cardiovascular deaths (46,000—179,900) associated with 2009 pandemic influenza A H1N1. 80% of the respiratory and cardiovascular deaths were in people younger than 65 years and 51% occurred in Southeast Asia and Africa.’ So, its apparent that even a mild version of the flu can result in very high mortality and morbidity rates, if it also happens to be highly infectious!

Now consider the so-call Bird Flu or as it’s most scientifically known, Type A H5N1. This flu is a true killer, killing as many as 50% of the people who contract it! That’s why it’s also referred to a HPAI which stands for Highly Pathogenic Avian Influenza.

Thankfully, HPAI does not spread very easily to humans…at least not yet. Recent studies have indicated that the virus is contained mostly to birds at this time. However, they’ve also indicated that this particular version may be just a few mutations (or genetic tweaks) away from becoming an airborne Fluageddon! (A situation that could develop if it manages to gain the contagiousness of the Swine flu while retaining its high level of pathogenicity)!

Such a flu, should it be let loose on the world, would make the movie Contagion seem like a walk in the park! Imagine catching a ‘cold’ where you had only a fifty-fifty chance of survival! Imagine a ‘cold’ so infectious that tens of millions came down with it all in a short time. Emergency services, hospitals and clinic would be almost instantly overwhelmed. Key personnel who maintain essential services like gasoline, electricity and water might easily abandon their posts setting up instances of widespread outages that would only fuel a growing panic. Such a dastardly flu could easily topple governments and start wars all across the globe….

But, what are the chances of this ever happening, you might well ask? I don’t think anyone does, but I’ll tell you this! The World Health Organization along with the CDC are growing increasingly uneasy as time goes on. One article, How Worried Should We Be’ published in Nature describes some of the reasons behind their concern.

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Sunday, September 18, 2011

That old Avian Flu is still hanging around!



“Greetings from The Humungus!
The Lord Humungus! The Warrior of the Wasteland!
The Ayatollah of Rock and Rolla!”
Mad Max 1981


While the Avian flu may or may not be a true 'Humungus', it is definitely on the watch list of many virologists worldwide. Unlike previous strains of influenza that have come and gone over the past decade (the swine flu comes to mind), this little bugger has proven to be pretty sly. Designated as a type A( H5N1) strain that reached a peak in over 63 countries in 2006, this novel strain was thought to be stamped out due to the extensive culling ($20 billion worth) of domestic poultry. The virus, which has other ideas, has managed to make a comeback in wild birds and is now considered to be endemic in Asia once again.To make matters worst, its also spreading with the wild bird population.

One item that also has scientists concerned is the newly acquired ability of the bug to resist current vaccines. This combined with a virulence factor that leaves about 60% of its victims dead and you can see why. All that is needed now will be for this strain to mutate to the point where it can be transmitted from human to human instead of just bird to bird. A process that previous stains have some to be adept at doing. Truly something for everyone to be a little concerned with as we head in to the 2011-12 winter season. Next weeks post: A(H7N7) - this one infects people, birds, pigs and even horses for God's sake!